IRIB Normandy Rouen / Institute for Research and Innovation in Biomedicine

  Research and Services Laboratories

UR4358 - Glyco-MEV - Glycobiologie et Matrice Extra-Cellulaire Végétale


http://glycomev.univ-rouen.fr/
 https://hal-normandie-univ.archives-ouvertes.fr/GLYCOMEV

Head: Jean-Claude MOLLET

  Contact

UR 4358
Faculté des Sciences et Techniques
76821 Mont-Saint-Aignan Cedex
Phone: +33 235 14 6394
  jean-claude.mollet@univ-rouen.fr


  Keywords
STRUCTURAL ANALYSIS OF GLYCO-MOLECULES IN PLANTS AND MICRO-ALGAE, PLANT GROWTH AND CELL WALL, PLANT DEFENSE, PLANT-MICROORGANISM INTERACTIONS, ROOT EXUDATE, GLYCOSYLATION IN MICRO-ALGAE, PRODUCTION OF BIOPHARMACEUTICALS, MOLECULAR BIOLOGY AND BIOCHEMISTRY, MICROBIOLOGY, PHYSIOLOGY, CELL IMAGING

  Networks
Laboratoires communs

► Adhésion à des réseaux


  Research Topics

  Composition

  Facilities

  Activity

Research activities in the laboratory «Glycobiologie et Matrice Extracellulaire Végétale » aim at elucidating the function and biosynthesis of glycoproteins and polysaccharides in higher plants and microalgae. We focus mainly, through reverse genetic approaches, on the function of polysaccharides in relation with plant development and morphogenesis. Another aspect of our research activity deals with defence mechanisms occurring specifically in root border cells with the ultimate goal of identifying identify novel molecules able to stimulate the plant immunity against pathogens. Finally, we also investigate the protein glycosylation processing in higher plants and microalgae by studying N-glycan pathways, glycosyltransferase activities and their Golgi localisation. Since plants and microalgae synthesize N-glycans that are immunogenic in humans, the aim of this topic  is to engineer the endogenous processing to produce in glycoproteins carrying human-compatible glycosylation patterns. The laboratory has also gained an international recognition in the cell imaging of carbohydrate epitopes using both confocal and cryo-electron microscopies.


  Main contributions

  Latest publications

2017

2016

2015

2014

2013


  Other Scientific Productions
Brevets actifs

Last update: 2018/09/05

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76183 ROUEN Cedex
France

Direction :
contact@irib-normandy.fr

Secretariat :
secretariat@irib-normandy.fr

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