Research Team EA 4312 Rouen Normandie University, Ministry of Education and Research |
Laboratory of Microbiology Signals and Microenvironment |
LMSM |
HeadPr Marc G.J. Feuilloley Secretary: S Barral |
ContactEA 4312 LMSM Faculty of Science & Technology – IUT Evreux, 55 rue Saint Germain 27000 Evreux Phone: +33 232 29 1550 marc.feuilloley@univ-rouen.fr severine.barral@univ-rouen.fr |
Research Topics
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Composition
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Facilities
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ActivityThe central topic of LMSM is bacterial adaptation. The remarkable evolutionary success of bacteria is due to their capacity of detecting physical (temperature, osmotic pressure, …) and chemical signals (nutriments, bacterial communication factors, signals from eukaryotic organisms or host) present in their environment and to develop an optima adaptative response. Modifications affect both the microorganisms and their environment. In the human body, that contains more than 1 kg bacteria, the commensal microflora can be considered as a specific organ. The LMSM investigates this question by studying bacterial sensor systems involved in the detection of environmental signals and effectors responsible for bacterial dominance and virulence. These studies are realized using human and vegetal models. An important topic concerns the role of bacteria in the intestine-skin-brain triangle and the interactions between eukaryote neurohormones and bacterial communication systems. Other models are aimed at investigating the bacterial response to aerial pollutants and sub-lethal stress. These studies can lead to the proposal of new antibacterial tools, phytoprotection strategies or prophylactic procedures adapted to the microenvironment. |
Main Contributions
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Main Publications |